Table 1.

Main events and web-mediated notifications

• August 2005 (M0) left pneumonectomy

• December 2011 (M72) trifocal relapse in the right lung treated by SRS

• December 2014 (M108) 2nd relapse in the right lung treated by chemotherapy

• March 23, 2015 (M116) Inclusion in the Phase III trial

• April 13, 2015 (M117) web-alert due to a pulmonary embolism

• April 18, 2017 (M141) web alert due to a tumor progression in the right lung treated by immunotherapy

• May 30, 2017 (M142) tumor apparent progression (routine imaging)

• July 26, 2017 (M144) partial response to treatment

• January 2018 (M150) follow-up ongoing