“Chemical imbalances of the brain” and the four humors. As a simplification, a depiction of four of the most prominent types of psychopathology with a neurotransmitter often associated with each. As in the RDoC and the four humors schemes, proper mental health is conceptualized dimensionally, as a balance of the factors underlying each type of symptom. GABA, gamma-aminobutyric acid; RDoC, Research Domain Criteria.