Table 2.
Simplified diagnostic criteria of the International Autoimmune Hepatitis Group
| Parameter | Discriminator | Score |
| ANA or ASMA | ≥ 1:40 | + 11 |
| ≥ 1:80 | + 21 | |
| Anti-LKM | ≥ 1:40 | + 21 |
| Anti-SLA/LP | Any titer | + 21 |
| Total IgG | > ULN | + 1 |
| > 1.1 × ULN | + 2 | |
| Liver histology | Compatible with AIH | + 1 |
| Typical of AIH | + 2 | |
| Absence of viral hepatitis | No | 0 |
| Yes | + 2 |
1
Addition of all points for autoantibodies must be done, maximum 2 points allowed. Definite autoimmune hepatitis (AIH) ≥ 7; Probably ≥ 6. Typical histology for AIH: Each of the following should be present, interface hepatitis, plasma cell infiltrates, emperiopolesis, and hepatic rosette formation. Compatible liver histology: Chronic hepatitis with lymphocytic infiltrations without typical features as above. AIH: Autoimmune hepatitis; ANA: Antinuclear antibody; ASMA: Anti-smooth muscle antibody; Anti-LKM: Anti-liver kidney microsomal antibody; Anti-SLA/LP: Anti-soluble liver antigen/liver pancreas antibody[18].