Genetic Interaction Studies Indicate that Co-suppression of ncapg2 and nphp1 Results in Exacerbation of the Renal Phenotype
(A) Representative images of zebrafish larvae immunostained with Na+-K+ ATPase α-1 subunit antibody at 4 dpf. Right, lateral images of zebrafish pronephric tubules; left, the proximal convolution tubule is magnified. The blue line on the top left image indicates the diameter. The scale bar (yellow line) represents 50 μm.
(B) Quantification of the diameter of the renal tubule positioned just posterior to the proximal convolution (μm); n = 35–52 larvae/batch, repeated; p values were calculated with a Student’s t-test; ns = not significant; error bars represent standard error of the mean (SEM).