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. 2019 Feb;47(2):86–93. doi: 10.1124/dmd.118.083691

Fig. 3.

Fig. 3.

(A) qPCR analysis of Fgf15, Fxr, and Shp mRNAs in the ileum and Fxr and Shp mRNA expression in the liver from mice after 5 days of vehicle or BBR treatment. (B) qPCR analysis of mRNA encoding bile acid conjugation and transporters in the liver and ileum from mice after 5 days of vehicle or BBR treatment. Values are medians and interquartile ranges (n = 6 per group). *P < 0.05. Baat, bile acid-CoA: amino acid N-acyltransferase; Bacs, bile acid-CoA synthetase; Cdo, cysteine dioxygenase; Csad, cysteine sulfinic acid decarboxylase; Hnf4α1, hepatic nuclear factor 4α1; Ibabp, ileal bile acid-binding protein; Ibat, ileal bile acid transporter; Mrp, multidrug resistance-associated protein; Ntcp, Na+/taurocholate cotransporter Oatp, organic anion transporting protein; Ost, organic solute transporter.