Figure 5.

Bridges connect stars to clusters. (A) A schematic figure shows bridge hyperedges (blue) connect stars (peach) and clusters (pink). (B) Testing the intersection of hyperedges versus the null distribution where the nodal occupation is uniformly sampled from all brain regions (see Methods), we demonstrate that bridges are more likely to connect stars with clusters than expected ( $P<1\times {10}^{-20}$). Moreover, bridges are less likely to connect stars to other stars ( $P < 1\times {10}^{-20}$). [Color figure can be viewed at http://wileyonlinelibrary.com]