Table 1.

Schedule of Events (SOE)

Activities	Screening	Baseline	Day 14	Month 2	Month 4	Month 6	Month 9	Month 12	Month 18	Month 24
Visits
Eligibility assessment	x
Xpert MTB/RIF (Ultra) assay	x
Sputum smear and culture	x	x		x	x	x	(x)	(x)	(x)	(x)
Drug sensitivity testing		x
Demographic data		x
Clinical examination		x	x	x	x	x	x	x	x	x
Chest X-ray		x				x				x
Lung function assessment		x		x		x	x	x	x	x
ECG		x						x		x
Medical history (update)		x	x	x	x	x	x	x	x	x
TB treatment and adherence			x	x	x	x	(x)	(x)	(x)	(x)
Quality of life/patient’s cost questionnaire		x		x		x		x		x
HIV test (CD4 count)		x						x		x
Hepatitis B serology		x
Haematology and Biochemistry		x				x		x		x
Urine dip stick test		x		x	x	x
Blood storage for nested research studies		x	x	x	x	x	x	x
Sputum storage for nested research studies		x	x	x	x	x	(x)	(x)	(x)	(x)
Urine storage for nested research studies		x		x	x	x	(x)	(x)	(x)	(x)