Table 4.

Effects of ChondroT on serum levels of Creatinine (Cr), blood urea nitrogen (BUN), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) in hyperuricemic mice

Blood parameter	NC	HC	AP (mg/kg)	ChondroT (mg/kg)
			5	37.5	75	150
Creatinine (mg/dL)	0.20 ± 0.02	0.75 ± 0.04 ###	0.23 ± 0.01 **	0.50 ± 0.04	0.28 ± 0.02 *	0.23 ± 0.02 **
BUN (mg/dL)	23.62 ± 0.56	40.10 ± 1.21 ###	21.45 ± 0.96 ***	26.27 ± 0.58 *	22.95 ± 1.06 *	20.43 ± 0.74 ***
GOT (U/L)	48.67 ± 0.90	73.33 ± 3.95 ##	39.80 ± 0.92 ***	54.83 ± 1.90 *	46.00 ± 2.01 *	39.75 ± 2.56 **
GPT (U/L)	15.00 ± 1.58	28.00 ± 1.46	13.50 ± 0.91 *	24.17 ± 0.95	20.33 ± 1.29	15.00 ± 1.39 *

NC, normal control; HC, hyperuricemic control with potassium oxonate (300 mg/kg); AP, allopurinol (5 mg/kg). Values are mean ± standard error (S.E., n = 5). ^##P < 0.01 and ^###P < 0.001 compared with NC group; ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001 compared with HC group