Table 1.
Details of included articles
| Reference | Year | Authors | Title |
|---|---|---|---|
| [4] | 1983 | S.D. Folz et al | Chemotherapeutic treatment of naturally acquired generalized demodicosis. |
| [5] | 1995 | W.H. Miller et al | Clinical efficacy of increased dosages of milbemycin oxime for treatment of generalized demodicosis in adult dogs. |
| [6] | 1995 | Z. Ristic et al | Ivermectin for treatment of generalized demodicosis in dogs. |
| [7] | 2003 | B.R. Holm | Efficacy of milbemycin oxime in the treatment of canine generalized demodicosis: a retrospective study of 99 dogs (1995–2000) |
| [8] | 2005 | J. Heine et al | Evaluation of the efficacy and safety of imidacloprid 10% plus moxidectin 2.5% spot-on in the treatment of generalized demodicosis in dogs: results of a European field study. |
| [9] | 2006 | E.H. Delayte et al | Eficàcia das lactonas macrocìclicas sistemicas (ivermectina e moxidectina) na terapia da demodicidose canina generalizada. |
| [10] | 2007 | L.J. Fourie et al | Efficacy of a novel formulation of metaflumizone plus amitraz for the treatment of demodectic mange in dogs. |
| [11] | 2009 | L.J. Fourie et al | Comparative efficacy and safety of two treatment regimens with a topically applied combination of imidacloprid and moxidectin (Advocate) against generalised demodicosis in dogs. |
| [12] | 2010 | Murayama et al | Efficacy of weekly oral doramectin treatment in canine demodicosis. |
| [13] | 2000 | R. Wagner et al | Field efficacy of moxidectin in dogs and rabbits naturally infested with Sarcoptes spp., Demodex spp. and Psoroptes spp. mites. |
| [14] | 2013 | L.J. Fourie et al | Efficacy of a topical application of Certifect (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5,63% w/v) for the treatment of canine generalized demodicosis. |
| [15] | 2015 | J.H.C. Hutt | Treatment of canine generalized demodicosis using weekly injections of doramectin: 232 cases in the USA (2002–2012). |
| [16] | 2009 | T.E. Paterson et al | Treatment of canine-generalized demodicosis: a blind, randomized clinical trial comparing the efficacy of Advocate (Bayer Animal Health) with ivermectin. |
| [17] | 2014 | T.E. Paterson et al | Canine generalized demodicosis treated with varying doses of a 2.5% moxidectin + 10% imidacloprid spot-on and oral ivermectin: parasiticidal effects and long-term treatment outcomes. |
| [18] | 2015 | L.J. Fourie et al | Efficacy of orally administered fluralaner (Bravecto) or topically applied imidacloprid/moxidectin (Advocate) against generalized demodicosis in dogs. |
| 19 | 2016 | R.H. Six et al | Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis. |
| [20] | 2016 | F. Beugnet et al | Efficacy of oral afoxolaner for the treatment of canine generalised demodicosis |
| [21] | 2017 | D.E Snyder et al | Efficacy of lotilaner (Credelio™), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp. |
| [22] | 2018 | A.M.Cordero et al | Doramectin in the treatment of generalized demodicosis. |
| [23] | 2018 | C. Becskei et al | Efficacy and safety of sarolaner against generalized demodicosis in dogs in European countries: a non-inferiority study. |
| [24] | 2018 | L.Duangkaew et al | A field trial in Thailand of the efficacy of oral fluralaner for the treatment of dogs with generalized demodicosis. |