Table 4.
Efficacy of topical therapies against generalised demodicosis in dogs. Reference 14 is repeated twice because two different protocols were tested in the same study
| Reference | Therapy | Posology | Adverse effects | Treatment duration | Efficacy |
|---|---|---|---|---|---|
| [4] | AMITRAZ | From 3 to 6 applications at 14-days intervals. | 3 | 2 | 3 |
| [8] | IMIDACLOPRID+MOXIDECTIN | From 2 to 4 applications at 28-days intervals. | 3 | 2 | 3 |
| [11] | IMIDACLOPRID+MOXIDECTIN | Group 1 treated at 28-days intervals max 4 times; group 2 at 7-days intervals max 16 times. | 2 | 1 | 3 (Group 1) 3 (Group 2) |
| [14] | FIPRONIL + METHOPRENE + AMITRAZ | Group 1 treated at 28-days intervals; group 2 treated at 14-days intervals. | 3 | 2 | 3 (Group 1) 3 (Group 2) |
| [14] | METAFLUMIZONE + AMITRAZ | Group 3 treated at 28-days intervals. | 3 | 2 | 3 |
| [16] | IMIDACLOPRID+MOXIDECTIN | ADV1 treated monthly; ADV2 biweekly; ADV4 weekly. | 3 | 2 | 1 (ADV1) 2 (ADV2) AND 3 (ADV4) |
| [17] | IMIDACLOPRID+MOXIDECTIN | ADV1 treated monthly; ADV2 biweekly; ADV4 weekly. | 3 | 1 | 1 (ADV1) 2 (ADV2) AND 3 (ADV3) |
| [18] | IMIDACLOPRID+MOXIDECTIN | 3 applications at 28-days intervals. | 3 | 2 | 3 |
| [19] | IMIDACLOPRID+MOXIDECTIN | Weekly from day 0 to day 81. | 3 | 2 | 3 |
| [20] | IMIDACLOPRID+MOXIDECTIN | 4 applications at 14-days intervals. | 3 | 2 | 3 |
| [23] | IMIDACLOPRID+MOXIDECTIN | From 2 to 6 applications at 7 or 28-days intervals | 3 | 2 | 3 |