Table 1.
Demographic and Clinical Characteristics for Patients with UC
|
C. difficile Positive N = 34 |
C. difficile Negative N = 68 |
||||
|---|---|---|---|---|---|
| Factors | N | Median (P25, P75) | N | Median (P25, P75) | P value |
| Age (y) | 34 | 44.5 (29.0, 60.0) | 68 | 44.5 (29.0, 60.0) | 1.000 |
| Median duration from UC diagnosis to CDAB test (mo) | 34 | 27.0 (7.0, 108.5) | 68 | 36.0 (13.5, 117.0) | 0.467 |
| Number of bowel movements (times/d) | 34 | 7.0 (4.5, 10.0) | 68 | 7.0 (5.0, 10.0) | 0.947 |
| Factors | N | Mean ± SD | N | Mean ± SD | P value |
| BMI | 34 | 20.4745 ± 3.82787 | 68 | 21.2466 ± 4.10828 | 0.390 |
| Peripheral venous white blood cell (109/L) | 34 | 8.0676 ± 2.82308 | 68 | 8.0554 ± 2.95580 | 0.984 |
| Peripheral neutrophils (109/L) | 34 | 5.9118 ± 2.82888 | 68 | 5.5834 ± 2.70716 | 0.571 |
| Factors | N | Positive (%) | N | Negative (%) | |
| Male gender | 16 | 47.1 | 32 | 47.1 | 1.000 |
| Smoking status | 0.866 | ||||
| Cessation ≥6 mo | 2 | 5.9 | 7 | 10.3 | |
| Active smoker | 4 | 11.8 | 9 | 13.2 | |
| Alcohol use | 0.218 | ||||
| Cessation ≥6 mo | 3 | 8.8 | 6 | 8.8 | |
| Active use | 4 | 11.8 | 2 | 2.9 | |
| Diabetes | 3 | 8.8 | 7 | 10.3 | 1.000 |
| UC Truelove and Witts criteria | 0.517 | ||||
| Mild | 3 | 8.8 | 14 | 20.6 | |
| Moderate | 18 | 52.9 | 28 | 41.2 | |
| Severe | 13 | 38.2 | 26 | 38.2 | |
| Mayo score at colonoscopy | 0.622 | ||||
| 1 | 5 | 15.6 | 8 | 12.3 | |
| 2 | 10 | 31.3 | 28 | 43.1 | |
| 3 | 17 | 53.1 | 29 | 44.6 | |
| Distribution of UC | 0.811 | ||||
| Proctitis | 1 | 2.9 | 0 | 0.0 | |
| Left-sided colitis | 8 | 23.5 | 17 | 25.0 | |
| Extensive colitis | 25 | 73.5 | 51 | 75.0 | |
| History of surgery | 2 | 5.9 | 3 | 4.4 | 1.000 |
| Symptom-fever | 7 | 20.6 | 15 | 22.1 | 0.865 |
| Symptom-abdominal pain | 16 | 47.1 | 43 | 63.2 | 0.119 |
| Symptom-bleeding | 27 | 79.4 | 63 | 92.6 | 0.099 |
| Symptom-diarrhea | 29 | 85.3 | 65 | 95.6 | 0.113 |
| Dilation of colon | 0.990 | ||||
| No | 33 | 97.1 | 66 | 97.1 | |
| ≥6 cm | 1 | 2.9 | 1 | 1.5 | |
| ≥8 cm | 0 | 0.0 | 1 | 1.5 | |
| Subsequent surgery | 9 | 27.3 | 11 | 16.2 | 0.189 |
UC ulcerative colitis, CDAB Clostridium difficile toxins A and B, SD standard deviation