Fig. 4.

The relative expression of miR-103a-3p/miR-382-5p in GECs and miR-103a-3p/miR-382-5p regulated the viability, migration and tube formation of GECs. a-b The relative expression of miR-103a-3p/miR-382-5p in AECs and GECs were detected by qRT-PCR. U6 was used as an inner control. Data represent means ± SD (n = 3, each group). **P < 0.01 vs. AECs group. c-d The effects of miR-103a-3p/miR-382-5p on the viability of GECs were determined by CCK-8 assay. Values are means ± SD (n = 5, each group). *P < 0.05, **P < 0.01 vs. miR-103a-3p/miR-382-5p (+) NC group; ^##P < 0.01 vs. miR-103a-3p/miR-382-5p (−) NC group. e-f The effects of miR-103a-3p/miR-382-5p on the migration of GECs by Transwell assay. Values are means ± SD (n = 5, each group). **P < 0.01 vs. miR-103a-3p/miR-382-5p (+) NC group; ^##P < 0.01 vs. miR-103a-3p/miR-382-5p (−) NC group. Scale bar represents 30 μm. g-h The effects of miR-103a-3p/miR-382-5p on the tube formation of GECs were evaluated by Matrigel tube formation assay. Values are means ± SD (n = 5, each group). **P < 0.01 vs. miR-103a-3p/miR-382-5p (+) NC group; ^##P < 0.01 vs. miR-103a-3p/miR-382-5p (−) NC group. Scale bar represents 30 μm