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. 2019 Jan 8;20:5. doi: 10.1186/s12863-018-0707-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Validation of our proposed panel of 32 AIMs. a. Correlations between gold standard PC1 and PC1 calculated using our subset of 32 AIMs and three previously published panels of AIMs. b. Correlation between P values obtained from association analysis corrected for gold standard PC1 and PC2 and P values obtained from association analyses corrected for PC1 and PC2 calculated using our subset of 32 AIMs, as well as from association analysis corrected for PC1 and PC2 using three previously published panels of AIMs. c. P values obtained from previously well-known T2D risk variants when association analyses were corrected for population stratification using gold standard PC1 and PC2, as well as PC1 and PC2 calculated from either our subset of 32 AIMs or three previously published panels of AIMs. d. Correlations between gold standard PC1 and PC1 calculated using our subset of 32 AIMs and three previously published panels of AIMs using several sample sizes. e. Map of the four geographic regions of Mexico and the ancestry proportions for each one. f. Correlations between gold standard PC1 and PC1 calculated using our subset of 32 AIMs and three previously published panels of AIMs using the four geographic regions of Mexico. GS: Gold Standard