Table 4.
Summary statistics of worm recovery in CcR3 KO mice within 30 days
| Experimental groups | Statistics | Recovery time (days) | AUC (%) | |||
|---|---|---|---|---|---|---|
| 5 | 10 | 15 | 20 | |||
| Control (n = 7)a | Mean | 31.1 | 21.5 | 8.8 | 16.5 | 23.9 |
| Geometric mean | 22.4 | 11.8 | 4.2 | 7.1 | 21.3 | |
| Median | 35.5 | 14.5 | 5.5 | 12.0 | 20.8 | |
| SD | 18.05 | 26.1 | 9.6 | 19.6 | 11.9 | |
| 10 mg/kg FLBZ (s.c., single dose, n = 7)a | Mean | 2.1 | 0 | 0 | 0 | 8.7 |
| Median | 2.5 | 0 | 0 | 0 | 8.8 | |
| Geometric mean | 1.5 | 0 | 0 | 0 | 8.7 | |
| SD | 2.1 | 0 | 0 | 0 | 0.4 | |
| Mann-Whitney rank sum test | U | 28 | – | – | – | 4 |
| P-value | 0.0156 | – | – | – | 0.01052 | |
Abbreviations: AUC area under the curve, n number of animal per group, FLBZ flubendazole, – not computed, SD standard deviation
aSeven animals were dissected at each time point except on days 10 and 20, where 5 were dissected