Figure 2.

Distribution of EV studies based on the isolation method A histogram depicting the distribution of isolation methods employed by the EV studies catalogued in Vesiclepedia is depicted. Differential centrifugation has been used by >73% of the studies to isolate EVs while 57.7% of the studies have used ultracentrifugation. Although the data is depicted as individual methods, most studies have employed a combination of these methods. For instance, filtration accounted for 34% of the EV studies and is always used in conjunction with other procedures to isolate EVs.