Figure 1.

Framework to construct POSTAR2 database. (A) POSTAR2 covers six species including human, mouse, fly, worm, Arabidopsis and yeast. (B) POSTAR2 provides three modules: (i) ‘RBP’ module, which provides annotations and functions of RBPs, as well as RBP-binding sites; (ii) ‘RNA’ module, consisting of several sub-modules including ‘Binding sites’, ‘Crosstalk’, ‘Variation’ and ‘Disease’, which annotates the RBP-binding sites using various regulatory events and genomic variants; (iii) ‘Translatome’ module, which aims for exploring the translation landscape of genes across different tissues and cell lines. (C) POSTAR2 provides a user-friendly interface for searching and visualization such as table views, network views, histograms and heatmaps.