Table 1.

RetroRules database content regarding the number of distinct reaction rules available at each diameter and depending whether or not stereochemistry is expressed in the reaction rules. The ‘All reaction rules’ column is the number of unique reaction rules from the two datasets

Diameter	Number of distinct reaction rules
	Dataset not expressing stereochemistry	Dataset expressing stereochemistry	All reaction rules
2	18 607	23 391	39 016
4	24 241	28 906	49 933
6	27 686	31 734	56 544
8	29 276	33 128	59 770
10	30 158	33 944	61 627
12	30 762	34 519	62 854
14	31 219	34 932	63 786
16	31 559	35 258	64 453