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. 2018 Sep 12;47(Database issue):D874–D880. doi: 10.1093/nar/gky821

Figure 1.

Figure 1.

Overview and workflow of AWESOME. The database integrates genomic information and PTM database/tools to annotate missense SNPs that potentially affect PTM. We downloaded all missense SNPs from dbSNP (138), then mapped these SNPs to canonical protein sequence via VEP and ‘biomaRt’ package in R. Four experimental PTM database were applied to annotate PTM-related SNPs. Twenty bioinformatics tools were applied to predict PTM-related SNPs. All of the results were rearranged and scored, and then presented at the website.