Table 1.
Overview of sQTLs in each cancer type included in SplicingQTL
| Cancer type | Disease full name | No. of Sample | No. of genotype | No. of splicing | sQTLs | Affected splicing | sQTL pairs | Survival_ sQTLs | GWAS_ sQTLs |
|---|---|---|---|---|---|---|---|---|---|
| ACC | Adrenocortical carcinoma | 77 | 3567953 | 26620 | 17752 | 913 | 24950 | 7 | 4930 |
| BLCA | Bladder urothelial carcinoma | 406 | 4183896 | 32125 | 168597 | 6180 | 289420 | 157 | 44333 |
| BRCA | Breast invasive carcinoma | 1090 | 2746175 | 38428 | 253767 | 11961 | 506672 | 64 | 64008 |
| CESC | Cervical squamous cell carcinoma and endocervical adenocarcinoma | 250 | 4272427 | 33443 | 118989 | 4847 | 190429 | 412 | 31143 |
| CHOL | Cholangiocarcinoma | 36 | 4012151 | 31208 | 64 | 9 | 64 | 0 | 5 |
| COAD | Colon adenocarcinoma | 285 | 4491421 | 27466 | 152518 | 6048 | 255470 | 294 | 39233 |
| DLBC | Lymphoid neoplasm diffuse large B-cell lymphoma | 48 | 4845460 | 26277 | 4445 | 206 | 5641 | 0 | 1254 |
| ESCA | Esophageal carcinoma | 180 | 4463210 | 43937 | 138960 | 5324 | 214082 | 764 | 36443 |
| GBM | Glioblastoma multiforme | 150 | 4556997 | 38904 | 126023 | 4724 | 197274 | 817 | 33604 |
| HNSC | Head and neck squamous cell carcinoma | 499 | 4247759 | 35648 | 236904 | 8109 | 418356 | 698 | 60692 |
| KICH | Kidney chromophobe | 66 | 3771773 | 39171 | 25251 | 1329 | 34571 | 388 | 6542 |
| KIRC | Kidney renal clear cell carcinoma | 527 | 4579516 | 39696 | 325766 | 10887 | 600508 | 493 | 80279 |
| KIRP | Kidney renal papillary cell carcinoma | 290 | 4894174 | 33438 | 162228 | 6001 | 264080 | 1115 | 41681 |
| LAML | Acute myeloid leukemia | 122 | 5120270 | 29804 | 35478 | 1348 | 51024 | 152 | 11042 |
| LGG | Lower grade glioma | 514 | 4632416 | 41896 | 354837 | 11254 | 675128 | 1062 | 85201 |
| LIHC | Liver hepatocellular carcinoma | 369 | 4156507 | 26210 | 119209 | 4407 | 194309 | 229 | 30134 |
| LUAD | Lung adenocarcinoma | 512 | 4383840 | 37236 | 255517 | 8777 | 455348 | 147 | 67226 |
| LUSC | Lung squamous cell carcinoma | 500 | 3742393 | 39640 | 242335 | 9123 | 437645 | 65 | 62268 |
| MESO | Mesothelioma | 87 | 4784881 | 36010 | 49305 | 1734 | 68126 | 809 | 13856 |
| OV | Ovarian serous cystadenocarcinoma | 293 | 2975439 | 41415 | 149571 | 6769 | 254127 | 133 | 39361 |
| PAAD | Pancreatic adenocarcinoma | 176 | 4985375 | 39104 | 140937 | 4946 | 224001 | 771 | 37996 |
| PCPG | Pheochromocytoma and Paraganglioma | 168 | 4707250 | 34321 | 112116 | 4400 | 180122 | 1156 | 29132 |
| PRAD | Prostate adenocarcinoma | 485 | 4823458 | 37654 | 313993 | 10268 | 581617 | 1643 | 75506 |
| READ | Rectum adenocarcinoma | 93 | 4516897 | 29274 | 52896 | 2064 | 76387 | 204 | 14965 |
| SARC | Sarcoma | 248 | 4081096 | 33922 | 124542 | 4944 | 202118 | 737 | 33246 |
| SKCM | Skin cutaneous melanoma | 101 | 4865378 | 34942 | 53912 | 2014 | 74913 | 280 | 15180 |
| STAD | Stomach adenocarcinoma | 408 | 4306085 | 41433 | 207947 | 7311 | 338590 | 280 | 53307 |
| TGCT | Testicular germ cell tumors | 144 | 4791125 | 35758 | 107451 | 3815 | 166457 | 305 | 28328 |
| THCA | Thyroid carcinoma | 493 | 4870332 | 39754 | 359916 | 11265 | 683697 | 1842 | 86793 |
| THYM | Thymoma | 107 | 4892278 | 33234 | 85317 | 3203 | 132081 | 935 | 23473 |
| UCEC | Uterine corpus endometrial carcinoma | 166 | 4941208 | 24707 | 61884 | 2773 | 92641 | 372 | 16929 |
| UCS | Uterine carcinosarcoma | 56 | 3888384 | 32022 | 6586 | 393 | 8485 | 25 | 1729 |
| UVM | Uveal melanoma | 80 | 4737551 | 32067 | 34585 | 1348 | 47524 | 716 | 10313 |