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. 2018 Nov 16;47(Database issue):D433–D441. doi: 10.1093/nar/gky1159

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Adding disease mutations to lollipop plots. (A) The lollipop plot displays PTM sites and disease-associated SNPs (purple squares) on human SHP-2. The inclusion of disease-associated SNPs yields an additional purple vertical axis reflecting the minor allele frequency (MAF), if available. Hovering the mouse over squares yields the display of further details about the disease SNP. (B) Analogously, hotspot mutations from TCGA can be visualized as red squares. In this case the additional vertical axis (red) reflects the total number of tumors having the specified mutation.