TABLE 3.

Comparison of Clinical Features Between NLPHL Patients With and Without Atypical T cells

Characteristic	NLPHL With T-Cell Atypia	NLPHL Without T-Cell Atypia	p
N	11	24	—
Sex
Male	9 (81.8%)	19 (79.2%)	NS
Female	2 (18.2%)	5 (20.8%)
Male:female ratio	4.5	3.8
Median age (range)
All patients	13.8 (6–66)	36.1 (12–73)	0.015
Male	12.2 (6–32)	35.2 (12–59)	0.002
Female	39.9 (13–66)	37.1 (18–73)	NS
Predominant site of nodal involvement			0.015*
Cervical	6 (54.5%)	2 (8.3%)
Submental/	2 (18.2%)	3 (12.5%)
submandibular
Inguinal	2 (18.2%)	7 (29.2%)
Axillary	1 (9.1%)	5 (20.8%)
Parotid	0 (0%)	4 (16.7%)
Retroperitoneal	0 (0%)	2 (8.3%)
Abdominal	0 (0%)	1 (4.2%)
Relapse of NLPHL	5/7 (71.4%)	3/22 (13.6%)	0.008

NS, not statistically significant.

^*P value reflects frequency of cervical involvement vs. all other nodal sites of disease.