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. Author manuscript; available in PMC: 2019 Feb 2.

Published in final edited form as: Chembiochem. 2017 Dec 18;19(3):272–279. doi: 10.1002/cbic.201700428

Figure 5. — A) Annimycin B chemical structure; B) The proposed biosynthesis of Annimycin B. The arrows depict the sequential synthesis of Annimycin^[18]; the dotted arrows depict the module-skipping biosynthesis pathway leading to Annimycin B; C) HPLC chromatograms of the metabolites from S. asterosporus DSM 41452::pKC1132-InAnn3 and S. asterosporus DSM 41452::pUC19Δ3100spec at 340 nm. Annimycin B is marked by the red line.

Figure 5. — A) Annimycin B chemical structure; B) The proposed biosynthesis of Annimycin B. The arrows depict the sequential synthesis of Annimycin^[18]; the dotted arrows depict the module-skipping biosynthesis pathway leading to Annimycin B; C) HPLC chromatograms of the metabolites from S. asterosporus DSM 41452::pKC1132-InAnn3 and S. asterosporus DSM 41452::pUC19Δ3100spec at 340 nm. Annimycin B is marked by the red line.