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. 2018 Jul 23;2(3):031906. doi: 10.1063/1.5023410

TABLE II.

Model parameters used in the simulations.

Parameter Value Meaning
N 1000 Number of cells in simulation
ηs 1 Cell-substrate friction coefficient
ηc 0.1 Cell-cell friction coefficient
K 5 Area elastic modulus
A0 1 Preferred area
Λ 0.5 Cell-cell adhesion strength
k 2 Contractility constant
α 0.1 Persistence force strength
β 0.1 Persistence force decay
Gρ 0.5 Maximal activation rate for ρ
Dρ 0.1 Inactivation rate for ρ
GM 0.5 Maximal activation rate for M
DM 0.05 Inactivation rate for M
Ks 120 Half maximum response constant
n 2 Hill coefficient
t1 0.07 T1 transformation threshold