Table 1.
Detailed demographic data from participants with LMCI and AD from the J-ADNI cohort
| Characteristics | LMCI |
AD |
P value LMCI versus AD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Male | Female | Total | P value male versus female | Male | Female | Total | P value male versus female | ||
| Total, n (%) | 116 (49.6) | 118 (50.4) | 234 (100) | 64 (43.0) | 85 (57.0) | 149 (100) | .2099 | ||
| Average age years (SD) | 72.8 (5.9) | 72.9 (6.0) | 72.8 (5.9) | .8403 | 73.3 (5.8) | 73.8 (7.1) | 73.6 (6.6) | .6522 | .2253 |
| Family history of dementia, n (%) | 32 (27.6) | 28 (23.7) | 60 (25.6) | .5505 | 19 (29.7) | 23 (27.1) | 42 (28.2) | .8542 | .6356 |
| Educational years (SD) | 14.1 (2.9) | 11.9 (2.3) | 13.0 (2.8) | <.0001 | 13.7 (3.7) | 11.5 (2.3) | 12.4 (3.1) | <.0001 | .0663 |
| Educational level, n (%) | |||||||||
| 0–9 years | 12 (10.3) | 17 (14.4) | 29 (12.4) | <.0001 | 10 (15.6) | 21 (24.7) | 31 (20.8) | <.0001 | NA |
| 10–15 years | 43 (37.1) | 88 (74.6) | 131 (56.0) | 27 (42.2) | 58 (68.2) | 85 (57.0) | |||
| ≥16 years | 61 (52.6) | 13 (11.0) | 74 (31.6) | 27 (42.2) | 6 (7.1) | 33 (22.1) | |||
| Amyloid positive, n (%) | 39 (62.9) | 38 (69.1) | 77 (65.8) | .5596 | 37 (90.2) | 42 (89.4) | 79 (89.8) | 1 | <.0001 |
| Total available, n | 62 | 55 | 117 | 41 | 47 | 88 | |||
| APOE ε4 positive, n (%) | 57 (50.0) | 64 (54.2) | 121 (52.2) | .5992 | 41 (65.1) | 47 (55.3) | 88 (59.5) | .2417 | .2051 |
| Total available, n | 114 | 118 | 232 | 63 | 85 | 148 | |||
Abbreviations: AD, Alzheimer's disease; LMCI, late mild cognitive impairment; SD, standard deviation; NA, not available.