Table 3. Model Discrimination for Multicenter Models Using Different Data and Analytic Methods.
| Modeling Approach | AUC (95% CI)a |
|---|---|
| Using highest and lowest of all laboratory values and vital signs, logistic regression (baseline) | 0.831 (0.830-0.832) |
| Adding information from all observed laboratory values and vital signsb | 0.899 (0.896-0.902) |
| Adding NLP of clinical textc | 0.922 (0.916-0.924) |
Abbreviations: AUC, area under the receiver operating characteristic curve; NLP, natural language processing.
Calculated using nested 10-fold cross-validation; 95% CIs were computed using bootstrapping.
Adds measures of distribution, variability, and trajectory of laboratory values and vital signs to models already using the highest and lowest values.
Adds NLP to models already using all observed values and measures of distribution, variability, and trajectory of laboratory values and vital signs.