Table 4. Sensitivity Analysis of the Timing of Physical Therapy and Subsequent Opioid Use^a.

Pain Site	Any Opioid Use Between 91 and 365 d After Index Date						Change in Opioid Use Between 91 and 365 d After Index Date
	Physical Therapy Between 0 and 30 d After Index Date			Physical Therapy Between 31 and 90 d After Index Date			Physical Therapy Between 0 and 30 d After Index Date			Physical Therapy Between 31 and 90 d After Index Date
	aOR (95% CI)	P Value	aOR (95% CI)		P Value	aOR (95% CI)		P Value	aOR (95% CI)		P Value
Shoulder	0.84 (0.72-0.97)	.02	0.87 (0.76-0.98)		.03	−6.1 (−13.8 to 1.5)		.12	3.6 (−8.7 to 16.0)		.56
Neck	0.86 (0.80-0.94)	<.001	1.14 (0.99-1.30)		.06	−4.8 (−18.1 to 8.6)		.48	−12.7 (−22.8 to −2.6)		.01
Knee	0.89 (0.79-1.00)	.04	0.80 (0.72-0.89)		<.001	2.0 (−7.7 to 11.8)		.69	−21.1 (−31.3 to −10.9)		<.001
Low back	0.89 (0.84-0.94)	<.001	1.07 (0.97-1.17)		.16	−9.6 (−15.0 to −4.0)		.001	6.1 (−3.0 to 15.3)		.19

Abbreviation: aOR, adjusted odds ratio.

^aAll analyses shown are adjusted for sex, age, year of diagnosis, comorbidities (shown in Table 2), and amount of opioid use during the first 90 days after diagnosis.