Table 2. Clinical Interventions and Administered Therapies by Treatment Allocation.
| Variable | Saline Placebo (n = 75) | Low-Dose Levocarnitine, 6 g (n = 35) | Medium-Dose Levocarnitine, 12 g (n = 34) | High-Dose Levocarnitine, 18 g (n = 106) | P Value |
|---|---|---|---|---|---|
| Fluids administered, mean (SD), L | |||||
| 24 h Before enrollment | 3.80 (2.11) | 4.02 (2.92) | 4.40 (3.08) | 3.94 (2.66) | .77 |
| 6 h After initiation of hemodynamic resuscitation | 3.39 (6.00) | 3.12 (1.86) | 2.74 (1.90) | 2.52 (1.89) | .50 |
| Mechanical ventilation | |||||
| No. (%) | 55 (73.3) | 29 (82.9) | 23 (67.6) | 78 (73.6) | .54 |
| Total time, median (IQR), h | 113.1 (64.0-252.6) | 127.8 (53.7-210.3) | 161.5 (46.0-306.7) | 98.6 (41.7-191.8) | .46 |
| Corticosteroids, No. (%) | 28 (37.3) | 14 (40.0) | 17 (50.0) | 40 (37.7) | .64 |
| Hemodialysis, No. (%) | 16 (21.3) | 4 (11.4) | 2 (5.9) | 16 (15.1) | .18 |
Abbreviation: IQR, interquartile range.