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. 2018 Jun 22;1(2):e180450. doi: 10.1001/jamanetworkopen.2018.0450

Table 1. Characteristics Associated With Chronic Opioid Use Among Medicare Part D Enrollees in 2015a.

Enrollee Characteristics Enrollees, No. (%) (N = 3 764 361) Enrollees With ≥90-d Prescription for Opioids, No. (%) (n = 522 180)a OR (95% CI)
Original reason for entitlement (age <65 y)
Disabled 657 010 (17.4) 175 897 (26.8) 3.10 (3.08-3.13)
ESRD 22 304 (0.6) 5266 (23.6) 1.84 (1.78-1.90)
Original reason for entitlement (age ≥65 y)
Reached age 65 y 2 735 152 (72.7) 249 873 (9.1) 1 [Reference]
Disabled 342 902 (9.1) 89 911 (26.2) 2.72 (2.70-2.75)
ESRD 6994 (0.2) 1233 (17.6) 1.37 (1.29-1.46)
Sex
Male 1 481 353 (39.3) 176 060 (11.9) 1 [Reference]
Female 2 283 007 (60.6) 346 120 (15.2) 1.46 (1.45-1.47)
Race/ethnicity
Non-Hispanic white 3 053 688 (81.1) 421 615 (13.8) 1 [Reference]
Non-Hispanic black 351 985 (9.3) 61 480 (17.5) 0.83 (0.82-0.84)
Hispanic 198 778 (5.3) 25 877 (13.0) 0.75 (0.74-0.76)
Other 159 910 (4.2) 13 208 (8.3) 0.61 (0.60-0.63)
Dual eligibility
Yes 1 028 725 (27.3) 231 713 (22.5) 1.38 (1.37-1.39)
No 2 735 635 (72.7) 290 467 (10.6) 1 [Reference]
Comorbidities, No.
0 1 324 141 (35.2) 98 788 (7.5) 1 [Reference]
1 1 004 673 (26.7) 127 941 (12.7) 1.73 (1.72-1.75)
2 607 431 (16.1) 101 001 (16.6) 2.31 (2.29-2.34)
≥3 828 115 (22.0) 194 450 (23.5) 3.64 (3.61-3.67)
Intraclass correlation coefficient Null model Adjusted model
County level, % 10.90 9.35

Abbreviations: ESRD, end-stage renal disease; OR, odds ratio.

a

Results are from a multilevel analysis, including Medicare enrollees and counties, adjusted for the individual characteristics of the Medicare enrollees listed in the Table, but not including any county characteristics (ie, a null model). Model includes 3118 US counties.