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. 2018 Jun 8;1(2):e180243. doi: 10.1001/jamanetworkopen.2018.0243

Table 2. Antibiotic Prescribing by Diagnostic Category Tier Among Patients With Acute Respiratory Infections in the 2013-2014 and 2014-2015 Influenza Seasons at Ambulatory Care Settings Affiliated With the US Influenza Vaccine Effectiveness Networka.

Diagnosis Patients, No. (%)
All Ages Pediatric Adult
Total (N = 14 987)b Prescribed Antibiotic (n = 6136)c Total (n = 5700)b Prescribed Antibiotic (n = 2173)c Total (n = 9287)b Prescribed Antibiotic (n = 3963)c
Tier 1: antibiotics almost always indicated 467 (3) 416 (89) 218 (4) 187 (86) 249 (3) 229 (92)
Pneumonia 447 (3) 400 (89) 202 (4) 174 (86) 245 (3) 226 (92)
Miscellaneous bacterial infections 20 (0.1) 16 (80) 16 (0.3) 13 (81) 4 (0.04) 3 (75)
Tier 2: antibiotics potentially indicatedd 5129 (34) 3198 (62) 2322 (41) 1445 (62) 2807 (30) 1753 (62)
Pharyngitis 2494 (17) 1000 (40) 1167 (20) 439 (38) 1327 (14) 561 (42)
Sinusitis 1707 (11) 1385 (81) 243 (4) 192 (79) 1464 (16) 1193 (81)
Suppurative otitis media 1212 (8) 1055 (87) 993 (17) 881 (89) 219 (2) 174 (79)
Tier 3: antibiotics not indicatede 9391 (63) 2522 (27) 3160 (55) 541 (17) 6231 (67) 1981 (32)
Viral upper respiratory tract infection 5553 (37) 1376 (25) 1964 (34) 299 (15) 3589 (39) 1077 (30)
Bronchitisf 1157 (8) 730 (63) 107 (2) 74 (7) 1050 (11) 656 (62)
Allergy or asthma 1217 (8) 289 (24) 451 (8) 61 (14) 766 (8) 228 (30)
Influenza diagnosis codeg 1257 (8) 167 (13) 317 (6) 43 (14) 940 (10) 124 (13)
Viral pneumonia 3 (0.02) 2 (67) 2 (0.04) 1 (50) 1 (0.01) 0
Remaining codes not listed elsewhere 1463 (10) 373 (25) 602 (11) 113 (19) 861 (9) 260 (30)
a

The diagnostic category tiers are adapted from Fleming-Dutra et al2 and Shapiro et al.14 The first 4 International Classification of Diseases, Ninth Revision diagnostic codes were examined. Each patient was classified in a tier; priority was given to tier 1 diagnoses, then tier 2 diagnoses, then tier 3 diagnoses. However, individuals could be in more than 1 diagnosis category.

b

Percentage indicates the percentage in the column.

c

Percentage indicates the percentage in the row.

d

Excludes patients with any tier 1 diagnosis.

e

Excludes patients with any tier 1 or tier 2 diagnosis.

f

Excludes 31 adults with a history of chronic obstructive pulmonary disease per medical record or who had a chronic obstructive pulmonary disease diagnosis code. If these are included, 684 of 1081 adults (63%) with a diagnosis of bronchitis received antibiotics.

g

Indicates an International Classification of Diseases, Ninth Revision code diagnosis of influenza, not laboratory confirmation of influenza, which was performed for research purposes only.