Table 1. Characteristics of Patients Initiating Dabigatran (150 mg), Rivaroxaban (20 mg), or Warfarin Within 90 Days of Initial Diagnosis of Atrial Fibrillation.
| Characteristic | No. (%) | ||
|---|---|---|---|
| Dabigatran 150 mg (n = 21 979) | Rivaroxaban 20 mg (n = 23 177) | Warfarin (n = 101 715) | |
| Demographics | |||
| Age, mean (SD) | 75.83 (6.4) | 75.75 (6.4) | 78.45 (7.2) |
| >85 y | 2348 (10.7) | 2471 (10.7) | 22 827 (22.4) |
| Female | 11 239 (51.1) | 11 571 (49.9) | 58 327 (57.3) |
| Dual Medicaid enrollment | 3740 (17.0) | 3204 (13.8) | 24 412 (24.0) |
| Race, % | |||
| White | 19 723 (89.7) | 21 019 (90.7) | 88 544 (87.1) |
| Black | 768 (3.5) | 744 (3.2) | 5420 (5.3) |
| Hispanic | 824 (3.7) | 851 (3.7) | 4689 (4.6) |
| Other | 664 (3.0) | 563 (2.4) | 3062 (3.0) |
| Comorbid conditions | |||
| Heart failure | 5310 (24.2) | 5405 (23.3) | 37 698 (37.1) |
| Cardiomyopathy | 1468 (6.7) | 1673 (7.2) | 9752 (9.6) |
| Other dysrhythmia | 7133 (32.5) | 7738 (33.4) | 36 489 (35.9) |
| Implantable device | 1036 (4.7) | 1282 (5.5) | 6742 (6.6) |
| Peripheral vascular disease | 4056 (18.5) | 4335 (18.7) | 25 507 (25.1) |
| Hypertension | 18 399 (83.7) | 19 548 (84.3) | 87 452 (86.0) |
| Diabetes | 7194 (32.7) | 7468 (32.2) | 38 040 (37.4) |
| Renal disease | 1977 (9.0) | 1868 (8.1) | 22 477 (22.1) |
| Liver disease | 861 (3.9) | 947 (4.1) | 4856 (4.8) |
| Stroke or TIA | 2638 (12.0) | 2679 (11.6) | 16 973 (16.7) |
| Previous major bleeding | |||
| Intracranial | 101 (0.5) | 102 (0.4) | 879 (0.9) |
| Gastrointestinal | 5577 (25.4) | 5999 (25.9) | 29 342 (28.8) |
| Medications in prior 90 d | |||
| Statin | 9842 (44.8) | 10 399 (44.9) | 44 000 (43.3) |
| Antiplatelet | 1074 (4.9) | 1136 (4.9) | 6452 (6.3) |
| PPIs | 4366 (19.9) | 4686 (20.2) | 22 117 (21.7) |
| NSAIDs | 2933 (13.3) | 2970 (12.8) | 11 667 (11.5) |
| Prior health services use | |||
| Prior inpatient hospital, mean (SD), d | 2.40 (4.9) | 2.36 (5.3) | 4.95 (8.6) |
| Skilled nursing facility | 846 (3.8) | 840 (3.6) | 9454 (9.3) |
| AF diagnosed during inpatient episode | 8940 (40.6) | 8942 (38.6) | 51 054 (50.2) |
Abbreviations: AF, atrial fibrillation; NSAIDs, nonsteroidal anti-inflammatory drugs; PPIs, proton pump inhibitors; TIA, transient ischemic attack.