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. Author manuscript; available in PMC: 2019 Jan 8.
Published in final edited form as: Histopathology. 2011 Apr 4;58(5):803–805. doi: 10.1111/j.1365-2559.2011.03829.x

Figure 2.

Figure 2.

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) with increased numbers of large cells (case 7). A, Areas of typical NLPHL with many singly scattered lymphocyte-predominant (LP) cells (inset) amidst a vaguely nodular background of lymphocytes and few histiocytes. B, Oct-2 stain highlights LP cells admixed with small B cells within nodules. C, Low-power view of CD15 stain showing numerous CD15+ LP cells in areas with increased numbers of large cells (**, bottom right) in contrast to adjacent areas of typical NLPHL clearly lacking CD15 expression (*, upper left). Only scattered granulocytes stain intensely in these latter areas. D, These cells are CD30) and strongly CD20+ (E). F, High-power view showing cytological atypia of the CD15+ large cells.