Fig. 3.
AM1710 increased phosphorylation of JNK 46/54 similarly in HEK cells stably expressing mCB2 and hCB2. (A) In HEK cells stably expressing mCB2, AM1710 increased phosphorylation of JNK 46/54 at 5 and 10 minutes, and CP55940 increased phosphorylation of JNK 46/54 only at 5 minutes. (B) In HEK cells stably expressing hCB2, AM1710 increased phosphorylation of JNK 46/54 at 5 minutes, and CP55940 increased phosphorylation of JNK 46/54 at 5 and 10 minutes. *P < 0.05 vs. vehicle; #P < 0.05 significant difference between CP55940 and AM1710. AU, arbitrary unit. n = 3 for each group.