Table 1. Adverse events caused by palbociclib.

	Grade 1	Grade 2	Grade 3	Grade 4
Gastrointestinal	16	7	0	0
HEENT	14	4	0	0
Constitutional	8	7	0	0
Hematologic
Neutropenia	1	2	2	1†
Thrombocytopenia	2	1	1†	0
Anemia	1	3	0	0
Musculoskeletal/Pain	9	2	1†	0
Pulmonary	7	2	0	0
Neurological	7	0	0	0
Dermatologic	5	1	0	0
Metabolic/Laboratory	1	0	1†	2†
Others	6	3	0	0

^†Adverse events in a single patient on high-dose simvastatin