Table 1. Demographic and clinical characteristics of the study population.
| "Never" | "Pyo" | OR [95% CI] | p-value * | |
|---|---|---|---|---|
| n = 303 | n = 1,827 | |||
| Age in 2013 (years) | 35 ± 13 | 31 ± 10 | 1.03 [1.02–1.04] | < 0.001 |
| Age at CF diagnosis (years) (MD = 25–121) | 20 ± 19 | 7 ± 12 | 1.05 [1.04–1.06] | < 0.001 |
| Male, n (%) | 167 (55) | 962 (53) | 1.10 [0.86–1.41] | 0.43 |
| BMI (kg/m2) (MD = 1–11) | 23 ± 4 | 21 ± 3 | 1.12 [1.09–1.16] | < 0.001 |
| F508del/F508del genotype, n (%) | 50 (17) | 812 (44) | 0.25 [0.18–0.34] | < 0.001 |
| Pancreatic insufficiency, n (%) | 165 (55) | 1552 (85) | 0.21 [0.16–0.27] | < 0.001 |
| Diabetes, n (%) | 14 (5) | 348 (19) | 0.21 [0.12–0.36] | < 0.001 |
| Aspergillosis, n (%) | 23 (8) | 288 (16) | 0.44 [0.28–0.68] | < 0.001 |
| FVC ≥ 80% predicted (MD = 7–17) | 222 (75) | 993 (55) | 2.47 [1.87–3.26] | < 0.001 |
| FEV1 ≥ 80% predicted (MD = 5–16) | 165 (55) | 480 (26) | 3.44 [2.68–4.42] | < 0.001 |
| Pneumothorax, n (%) | 3 (1) | 22 (1) | 0.82 [0.24–2.76] | 0.75 |
| Hemoptysis, n (%) | 23 (8) | 183 (10) | 0.74 [0.47–1.16] | 0.19 |
Values are expressed as n, n (%) or mean ± standard deviation
* p-values correspond to logistic regressions’p-values
MD = x-y means there was x missing data in “Never” and y in “Pyo”