Table 1.
ACC Metabolite Ratios to tCr and Reproducibility Measures
| Metabolites | Visit | Mean Ratio to tCr (StdDev) | Mean CRLB (%) | Mean CV (%) | Mean RD (%) | N |
|---|---|---|---|---|---|---|
| Cr | 1 | 0.49 (0.2) | 7.3 | 14.4 | 20.3 | 10 |
| 2 | 0.45 (0.07) | 7.6 | ||||
| GABA | 1 | 0.38 (0.1) | 8.4 | 17.7 | 21.9 | 10 |
| 2 | 0.34 (0.1) | 9.4 | ||||
| Gln | 1 | 0.25 (0.1) | 14.6 | 21.6 | 34.8 | 6 |
| 2 | 0.24 (0.07) | 12.9 | ||||
| Glu | 1 | 1.4 (0.2) | 2.9 | 7.9 | 10.2 | 10 |
| 2 | 1.29 (0.07) | 3.0 | ||||
| GSH | 1 | 0.24 (0.06) | 7.2 | 15.9 | 21.8 | 10 |
| 2 | 0.26 (0.02) | 7.4 | ||||
| mI | 1 | 0.71 (0.2) | 5.0 | 12.2 | 16.1 | 10 |
| 2 | 0.69 (0.1) | 5.0 | ||||
| NAA | 1 | 1.53 (0.1) | 1.9 | 5.3 | 7.4 | 10 |
| 2 | 1.46 (0.2) | 2.1 | ||||
| PCh | 1 | 0.26 (0.04) | 7.4 | 16.8 | 23 | 9 |
| 2 | 0.24 (0.06) | 7.1 | ||||
| PCr | 1 | 0.56 (0.07) | 5.6 | 8.4 | 11.7 | 9 |
| 2 | 0.55 (0.07) | 6.3 | ||||
| PE | 1 | 0.46 (0.07) | 7.1 | 10.2 | 14 | 10 |
| 2 | 0.45 (0.07) | 7.3 | ||||
| GPC+PCh | 1 | 0.28 (0.03) | 3.2 | 6.2 | 8.5 | 10 |
| 2 | 0.27 (0.05) | 3.5 | ||||
| NAA+NAAG | 1 | 1.63 (0.2) | 2.3 | 5.4 | 7.5 | 10 |
| 2 | 1.57 (0.2) | 2.3 | ||||
| Ins+Gly | 1 | 0.88 (0.2) | 3.5 | 10.2 | 13.2 | 10 |
| 2 | 0.81 (0.1) | 3.8 | ||||
| Glx | 1 | 1.63 (0.3) | 3.2 | 10.2 | 13.3 | 10 |
| 2 | 1.49 (0.1) | 3.6 |
ACC - anterior cingulate cortex; CV - coefficient of variation; CRLB - Cramer-Rao lower bound; RD - relative difference; StDev - standard deviation