. Author manuscript; available in PMC: 2020 Jan 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2018 Oct 17;28(1):76–82. doi: 10.1158/1055-9965.EPI-18-0654

Table 4.

Multiple regression analyses between adiposity and inflammation- and angiogenesis-related biomarker measurements adjusted for age, sex, and tumor stage

	VEGF-A (pg/L)		VEGF-D (pg/L)		CRP (mg/L)		SAA (mg/L)		sICAM-1 (mg/L)		sVCAM-1 (mg/L)
	β	p	β	p	β	p	β	p	β	p	β	p
BMI (kg/m²)	−0.02	0.28	−0.002	0.73	0.04	0.18	−0.0001	1.00	0.01	0.32	0.03	0.006
Subcutaneous fat area, L3/L4 (cm²)	−0.0003	0.65	0.000007	0.82	0.001	0.31	0.0004	0.79	0.0001	0.78	0.005	0.15
Subcutaneous fat area, L4/L5 (cm²)	−0.0003	0.64	−0.00003	0.92	0.001	0.38	0.001	0.66	0.000001	1.00	0.005	0.13
Visceral fat area, L3/L4 (cm²)	0.0001	0.16	0.001	0.68	0.003	0.02	0.00	0.04	0.10	0.21	0.15	0.07
Visceral fat area, L4/L5 (cm²)	0.001	0.13	0.0004	0.35	0.0039	0.02	0.003	0.09	0.001	0.10	0.001	0.036
Ratio 1: VFA:SFA at L3/L4	0.43	0.0006	0.015	0.80	0.53	0.053	0.66	0.007	0.15	0.04	0.06	0.33
Ratio 2: VFA:SFA at L4/L5	0.62	0.001	0.09	0.30	0.89	0.41	0.76	0.04	0.27	0.01	0.10	0.32

Abbreviations: cm, centimeters; VFA: visceral fat area; SFA: subcutaneous fat area; mg: milligrams; L: liters; VEGF-A: vascular endothelial growth factor A; VEGF-D: vascular endothelial growth factor D; CRP: C reactive protein; SAA: serum amyloid A; sICAM-1: soluble intracellular cell adhesion molecule 1; sVCAM-1: soluble vascular cell adhesion molecule 1; BMI: body mass index