Table 3.

Statistics of individual biomarkers in healthy controls, benign conditions and PDAC patients.

Biomarker	Subgroup	Number	Min	Max	Median	Mean	IQR
OPN	Healthy Control	89	2.1	21.7	6.9	7.9	4.2
	Chronic Pancreatitis	68	0.8	103.6	13.6	20.7	15.3
	IPMN	63	2.3	84.8	8.5	12.1	9.1
	PDAC early stage	96	2.0	135.3	14.3	19.1	15.5
	PDAC late stage	92	2.3	154.1	14.5	21.5	17.3
MIA	Healthy Control	89	0.1	1.5	0.6	0.7	0.5
	Chronic Pancreatitis	68	0.1	1.2	0.5	0.5	0.3
	IPMN	62*	0.1	1.5	0.6	0.6	0.4
	PDAC early stage	96	0.1	1.4	0.5	0.6	0.4
	PDAC late stage	92	0.3	2.1	0.6	0.7	0.4
CEACAM-1	Healthy Control	89	2.3	26.9	12.7	13.0	7.1
	Chronic Pancreatitis	68	5.2	93.2	17.1	23.4	16.7
	IPMN	63	5.7	35.4	16.1	17.0	9.8
	PDAC early stage	96	4.8	120.9	22.2	31.4	25.7
	PDAC late stage	92	4.6	117.8	21.9	29.3	18.9
MIC-1	Healthy Control	89	0.1	0.8	0.3	0.3	0.2
	Chronic Pancreatitis	68	0.2	3.4	0.9	1.0	0.9
	IPMN	63	0.3	3.0	0.7	0.8	0.6
	PDAC early stage	95*	0.4	7.9	1.1	1.5	1.0
	PDAC late stage	92	0.2	7.1	1.0	1.3	0.9
SPON1	Healthy Control	89	1.9	14.9	4.7	5.0	2.0
	Chronic Pancreatitis	68	1.0	17.5	5.9	6.3	3.2
	IPMN	63	0.6	21.8	5.2	5.9	2.7
	PDAC early stage	96	2.0	42.8	5.8	7.3	3.4
	PDAC late stage	92	2.1	21.1	5.9	6.5	3.2
HSP27	Healthy Control	89	0.2	4.2	0.9	1.2	0.9
	Chronic Pancreatitis	68	0.2	4.8	1.0	1.2	0.7
	IPMN	63	0.1	8.6	0.9	1.3	1.0
	PDAC early stage	96	0.2	7.1	1.2	1.5	1.5
	PDAC late stage	92	0.2	5.2	1.2	1.3	1.1
CA19–9	Healthy Control	89	<0.1	71.6	11.0	15.6	13.5
	Chronic Pancreatitis	68	<0.1	203.2	20.1	32.2	32.0
	IPMN	63	<0.1	386.	16.8	26.9	18.8
	PDAC early stage	96	<0.1	27027.8	85.3	827.5	583.2
	PDAC late stage	92	<0.1	25110.7	354.8	1638.7	1465.9

NOTE: all biomarkers are at ng/mL, except CA19–9 at U/mL. IQR, interquartile range.

^*, 2 missed data due to Out of Range.