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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Hepatology. 2018 Dec 17;69(1):343–358. doi: 10.1002/hep.30131

Figure 5.

Figure 5.

Effects of PXR activation on liver regeneration after PHx in WT mice. (A) Mice were treated with PCN or vehicle following surgery and sacrificed at the indicated time points. (B) Liver-to-body-weight ratios. **P < 0.01 and ***P < 0.001 compared with the vehicle group at the same time point. The data are expressed as the means ± SD (n = 6). (C) Representative gross pictures of mice livers after PCN administration for 2 days and 5 days. (D-G) Histopathological and IHC staining of representative mouse liver samples following H&E (D), CTNNB1 (E), KI67 (F), and SOX9 (G) staining.