Skip to main content
. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: Behav Brain Res. 2018 Dec 12;360:262–269. doi: 10.1016/j.bbr.2018.12.027

Figure 4. The involvement of α6 nAChRs in the antidepressant-like effects of bupropion in the FST.

Figure 4.

Effects of bupropion on immobility (A) and climbing (B) behavior in the FST in α6 KO mice and their WT littermates. After 30 min bupropion (3 and 10 mg/kg, s.c.) or vehicle (saline) injection, mice were exposed to the FST. Results are expressed as the mean ± S.E.M of 11 (WT) and 9 (KO) mice. * p < 0.05, significantly different from vehicle treated WT group; + p < 0.05, significantly different from vehicle treated KO group; # p < 0.05, significantly different from its corresponding control group (KO vs WT group). Bup: bupropion