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Response to treatment
| Response, n (%) | KRAS-positive (n = 206) | KRAS-negative (n = 324) | P-value |
|---|---|---|---|
| ORR | 41 (20) | 55 (17) | 0.39 |
| DCR | 96 (47) | 134 (41) | 0.23 |
| Best overall response | |||
| CR | 2 (1) | 1 (<1) | |
| PR | 39 (19) | 54 (17) | |
| SD | 55 (27) | 79 (24) | |
| PD | 88 (43) | 153 (47) | |
| Death | 12 (5) | 30 (9) | |
| Not determined | 10 (5) | 7 (2) | |
n number of patients, ORR objective response rate, DCR disease control rate, CR complete response, PR partial response, SD stable disease, PD progression disease
