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. 2018 Dec 21;63(1):e01754-18. doi: 10.1128/AAC.01754-18

TABLE 2.

Melting temperatures of apo- and holo-enzymes measured by thermal shift assay

Variant Mean ± SD
Tm (°C) ΔTm (°C)
NDM-1 Holo 56.6 ± 0.1 18.3 ± 0.1
Apo 38.3 ± 0.1
L3IMP Holo 55.3 ± 0.1 24.4 ± 0.4
Apo 30.9 ± 0.3
L3VIM Holo 55.2 ± 0.1 31.5 ± 0.1
Apo 23.7 ± 0.1
L3Pro Holo 52.5 ± 0.1 19.0 ± 0.2
Apo 33.5 ± 0.1