TABLE 6.
MIC distributions for plazomicin against gentamicin-susceptible and gentamicin-nonsusceptible Staphylococcus aureus and Staphylococcus epidermidis
| Organism (no. of isolates) and agenta |
No. of isolates (cumulative percentage of isolates) with the following plazomicin MIC (µg/ml): |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| ≤0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | >16 | |
| Staphylococcus aureus | |||||||||
| Gentamicin S (3,626) | 28 (0.8) | 262 (8.0) | 2,063 (64.9) | 1,157 (96.8) | 106 (99.7) | 10 (100) | |||
| Gentamicin NS (69) | 5 (7.2) | 29 (49.3) | 31 (94.2) | 3 (98.6) | 1 (100) | ||||
| Staphylococcus epidermidis | |||||||||
| Gentamicin S (240) | 204 (85.0) | 33 (98.8) | 3 (100) | ||||||
| Gentamicin NS (124) | 51 (41.1) | 64 (92.7) | 8 (99.2) | 1 (100) | |||||
a
S, gentamicin susceptible; NS gentamicin nonsusceptible.