TABLE 2.

Rates of spontaneous mutation frequency by echinocandin agent^a

Echinocandin agent	Median mutation frequency rate		P	Median mutation frequency rate		P
	Prior EC exposure (n = 10)	No prior EC exposure (n = 10)		CAS susceptible (n = 10)	CAS nonsusceptible (n = 10)
Anidulafungin	3.002 × 10−7	5.869 × 10−7	0.85	2.875 × 10−7	3.952 × 10−7	0.60
Caspofungin	1.096 × 10−5	1.022 × 10−5	0.91	1.787 × 10−5	3.038 × 10−5	0.28
Micafungin	5.777 × 10−9	2.465 × 10−9	0.79	5.777 × 10−9	2.465 × 10−9	0.91

^aEC, echinocandin; CAS, caspofungin.