TABLE 5.

Studies evaluating TP6076 against CRAB

Reference no.	β-Lactamase(s)	No. of CRAB isolates	No. of isolates with MIC >4 μg/ml	MIC data (μg/ml)
				MIC50	MIC90	Range
68		121		0.03	0.06	≤0.002–0.12
67	Overall	326	0a	0.06	0.125	0.008–0.5
	OXA-23	255
	OXA-40	23
	0XA-58	36
	OXA-51b	10
	NDM	1
141		41	0	0.008	0.063	002–0.25

^aAll isolates had MICs of <0.5 µg/ml.

^bOverexpressed.