Table 2.
Age | Lobule | Genotype | oEGL thickness (μm) | iEGL thickness (μm) | EGL thickness (μm) | No. of mice |
---|---|---|---|---|---|---|
P6 | III | Ctrl | 22.93 ± 1.338 | 12.2 ± 2.229 | 35.15 ± 2.028 | 4 |
cKO (mean ± SEM) | 21.03 ± 0.8518 | 12.33 ± 1.314 | 33.35 ± 0.5439 | 4 | ||
p | p = 0.2929 | p = 0.9462 | p = 0.3973 | |||
VI | Ctrl | 19.75 ± 2.395 | 11.9 ± 0.745 | 31.65 ± 2.042 | 4 | |
cKO (mean ± SEM) | 19.65 ± 0.8431 | 12.2 ± 1.602 | 31.85 ± 0.9314 | 4 | ||
p | p = 0.9554 | p = 0.8713 | p = 0.9246 | |||
VII | Ctrl | 25.63 ± 1.821 | 11.78 ± 1.287 | 37.4 ± 1.867 | 4 | |
cKO (mean ± SEM) | 20.25 ± 1.002 | 10.95 ± 1.056 | 31.23 ± 1.684 | 4 | ||
p | p = 0.005 | p = 0.6565 | p = 0.0062 | |||
VIII | Ctrl | 28.08 ± 0.3966 | 14.45 ± 1.156 | 42.53 ± 0.8835 | 4 | |
cKO (mean ± SEM) | 22.4 ± 1.391 | 12.53 ± 1.026 | 34.95 ± 1.427 | 4 | ||
p | p = 0.0033 | p = 0.3029 | p = 0.0011 | |||
X | Ctrl | 18.08 ± 0.4498 | 8.025 ± 0.8929 | 26.13 ± 1.26 | 4 | |
cKO (mean ± SEM) | 17.2 ± 0.4143 | 7.2 ± 1.042 | 24.35 ± 1.341 | 4 | ||
p | p = 0.6256 | p = 0.6565 | p = 0.4038 | |||
P11 | III | Ctrl | 6.650 ± 0.1443 | 6.625 ± 0.762 | 13.3 ± 0.8396 | 4 |
cKO (mean ± SEM) | 4.575 ± 0.3945 | 7.025 ± 0.792 | 11.55 ± 0.6702 | 4 | ||
p | p = 0.0009 | p = 0.6517 | p = 0.1012 | |||
VI | Ctrl | 9.925 ± 0.3376 | 9.025 ± 0.5218 | 18.98 ± 0.6223 | 4 | |
cKO (mean ± SEM) | 8.8 ± 0.3559 | 8.625 ± 0.2175 | 17.43 ± 0.4871 | 4 | ||
p | p = 0.0555 | p = 0.6517 | p = 0.1446 | |||
VII | Ctrl | 10.65 ± 0.4573 | 9.425 ± 0.625 | 20.08 ± 0.4871 | 4 | |
cKO (mean ± SEM) | 7.825 ± 0.5851 | 9.4 ± 0.3851 | 17.23 ± 0.9464 | 4 | ||
p | p < 0.0001 | p = 0.9775 | p = 0.0099 | |||
VIII | Ctrl | 7.975 ± 0.5006 | 9.375 ± 0.606 | 17.28 ± 0.3351 | 4 | |
cKO (mean ± SEM) | 5.1 ± 0.4564 | 10.03 ± 0.7087 | 14.98 ± 1.057 | 4 | ||
p | p < 0.0001 | p = 0.4645 | p = 0.0339 | |||
X | Ctrl | 5.725 ± 0.1931 | 4.9 ± 0.9531 | 10.6 ± 1.053 | 4 | |
cKO (mean ± SEM) | 4.95 ± 0.3594 | 5.525 ± 0.06292 | 10.48 ± 0.3224 | 4 | ||
p | p = 0.1800 | p = 0.4817 | p = 0.9047 | |||
P14 | III | Ctrl | 1.775 ± 0.0479 | 5.35 ± 0.02887 | 7.1 ± 0.09129 | 4 |
cKO (mean ± SEM) | 1.275 ± 0.04787 | 1.475 ± 0.1031 | 2.75 ± 0.119 | 4 | ||
p | p = 0.0446 | p < 0.0001 | p < 0.0001 | |||
VI | Ctrl | 5.525 ± 0.366 | 10.63 ± 0.3301 | 16.13 ± 0.275 | 4 | |
cKO (mean ± SEM) | 0.9 ± 0.09129 | 7.275 ± 0.1109 | 8.175 ± 0.06292 | 4 | ||
p | p < 0.0001 | p < 0.0001 | p < 0.0001 | |||
VII | Ctrl | 6.325 ± 0.2689 | 10.98 ± 0.275 | 17.33 ± 0.4626 | 4 | |
cKO (mean ± SEM) | 3.15 ± 0.06455 | 3.5 ± 0.2677 | 6.65 ± 0.2533 | 4 | ||
p | p < 0.0001 | p < 0.0001 | p < 0.0001 | |||
VIII | Ctrl | 6.125 ± 0.2056 | 6.6 ± 0.2449 | 12.73 ± 0.3038 | 4 | |
cKO (mean ± SEM) | 2.75 ± 0.0866 | 5.15 ± 0.2466 | 7.9 ± 0.2345 | 4 | ||
p | p < 0.0001 | p = 0.0001 | p < 0.0001 | |||
X | Ctrl | 1.15 ± 0.06455 | 7.575 ± 0.3351 | 8.75 ± 0.3227 | 4 | |
cKO (mean ± SEM) | 1.175 ± 0.08539 | 7.525 ± 0.2016 | 8.7 ± 0.1414 | 4 | ||
p | p = 0.9172 | p = 0.8816 | p = 0.8908 |