. 2019 Jan 2;39(1):63–77. doi: 10.1523/JNEUROSCI.2095-18.2018

Table 1.

Comparison of lipid and enzyme expression profiles among the mouse genotypes used in this study

Life expectancy	GalNAc-T enzyme expressed globally	CST enzyme expressed globally	Axonal complex ganglioside expression		Global a-series overexpression	Non-neuronal GM3 overexpression	Non-neuronal GD3 overexpression
Life expectancy	GalNAc-T enzyme expressed globally	CST enzyme expressed globally	a-series	b-series	Global a-series overexpression	Non-neuronal GM3 overexpression	Non-neuronal GD3 overexpression
WT	✓	✓	✓	✓	×	×	×
GalNAc-T^−/−	×	✓	×	×	×	✓	✓
CST^−/−	✓	×	✓	✓	×	×	×
CST^−/− × GalNAc-T^−/−-Tg (neuronal)	×	×	✓	✓	×	✓	✓
CST^−/− × GD3s^−/−	✓	×	✓	×	✓	×	×
CST^−/− × GalNAc-T^−/−-Tg(glial)	×	×	×	×	×	✓	✓
CST^−/− × GalNAc-T^−/−	×	×	×	×	×	✓	✓