Table 3.
Characteristic | No. | OS | DFS | ||||
---|---|---|---|---|---|---|---|
Adjusted HR* | 95% CI | P* | Adjusted HR* | 95% CI | P* | ||
Sex | |||||||
Male | 65 | Ref | .005 | Ref | .008 | ||
Female | 45 | 0.37 | 0.18-0.74 | 0.41 | 0.21-0.79 | ||
Donor type | |||||||
MRD | 51 | Ref | <.001 | Ref | <.001 | ||
MUD 10/10 | 44 | 1.43 | 0.70-2.95 | 2.38 | 1.21-4.68 | ||
mMUD | 15 | 8.32 | 3.47-19.93 | 6.30 | 2.69-14.74 | ||
MF | |||||||
Primary | 58 | Ref | .094 | Ref | .024 | ||
Secondary | 52 | 0.56 | 0.29-1.10 | 0.48 | 0.26-0.91 | ||
Cytogenetics | |||||||
Favorable | 67 | Ref | .001 | Ref | .008 | ||
Unfavorable | 24 | 2.31 | 1.05-5.07 | 1.39 | 0.66-2.94 | ||
VHR | 15 | 4.19 | 1.93-9.13 | 3.14 | 1.53-6.47 | ||
MIPSS70+ v2.0 classification† | |||||||
Intermediate risk | 11 | 0.29 | 0.04-2.26 | <.001 | 0.24 | 0.03-1.91 | <.001 |
High risk | 47 | Ref | Ref | ||||
VHR | 35 | 5.05 | 2.39-10.70 | 3.87 | 1.90-7.88 |
Based on the multivariable Cox regression model adjusting for sex, donor type, and cytogenetics.
Based on the multivariable Cox regression model adjusting for sex and donor type, but not for cytogenetics.