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. 2017 Apr 28;7(1):6475. doi: 10.4081/xeno.2017.6475

Table 1.

The treatment protocol of Betulinic acid, DMBA and I3C among the Sprague Dawley female rats assorted in 6 groups (n=6 for each group).

Groups Compound Concentration Treatment type
I Standard pellet diet and tap water ad libitum - Untreated Control
II DMBA 10 mg/kg bw Mutagen
III DMBA+ Betulinic acid 10 mg/kg bw + 2 mg/kg bw  
IV DMBA+ Betulinic acid 10 mg/kg bw + 5 mg/kg bw Treatment groups to check the inhibitory effect of test compound
V DMBA+ Betulinic acid 10 mg/kg bw + 10 mg/kg bw  
VI DMBA+ Indole-3-carbinol 10 mg/kg bw + 10 mg/kg bw