Table 1.
The treatment protocol of Betulinic acid, DMBA and I3C among the Sprague Dawley female rats assorted in 6 groups (n=6 for each group).
| Groups | Compound | Concentration | Treatment type |
|---|---|---|---|
| I | Standard pellet diet and tap water ad libitum | - | Untreated Control |
| II | DMBA | 10 mg/kg bw | Mutagen |
| III | DMBA+ Betulinic acid | 10 mg/kg bw + 2 mg/kg bw | |
| IV | DMBA+ Betulinic acid | 10 mg/kg bw + 5 mg/kg bw | Treatment groups to check the inhibitory effect of test compound |
| V | DMBA+ Betulinic acid | 10 mg/kg bw + 10 mg/kg bw | |
| VI | DMBA+ Indole-3-carbinol | 10 mg/kg bw + 10 mg/kg bw |