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. 2017 Apr 28;7(1):6475. doi: 10.4081/xeno.2017.6475

Table 4.

Modulation of DMBA induced impairment of antioxidant enzymes by betulinic acid among different treatment groups of female Sprague Dawley rats.

Parameter Group I Group II Group III Group IV Group V Group VI F-ratio HSD value
Superoxide Dismutase                
(IU/mg protein)                
     Stomach 16.085a±0.0001 51.090b±0.009 12.280c±0.008 17.003d±0.001 18.777e±0.016 29.237f±0.008 7.668* 0.00016
     Lung 13.640a±0.270 17.692b±0.0003 14.294c±0.022 13.964d±0.009 17.464e±0.014 11.252f±0.009 6.932* 0.0745
Catalase                
(IU/mg protein)                
     Stomach 39.364a±4.329 37.514b±3.896 10.021c±2.597 13.727d±4.218 10.259e±4.117 51.460f±4.210 17.516* 0.0058
     Lung 22.012a±12.987 8.509b±3.812 33.365b±12.884 15.597d±4.329 29.803e±4.310 24.3908f±5.316 45.584* 0.0122
Ascorbate Peroxidase                
(milli IU/mg protein)                
     Stomach 56.700a±0.021 73.30b±0.010 12.360c±0.024 28.210d±0.045 21.620e±0.044 53.90f±0.023 4.282* 0.0475
     Lung 21.370a±0.022 35.10b±0.021 26.630c±0.043 39.090d±0.047 45.040e±0.032 18.80f±0.020 11.870* 0.0136
Guaiacol Peroxidase                
(milli IU/mg protein)                
     Stomach 5.140a±0.001 17.760b±0.001 3.360c±0.003 3.950d±0.005 3.150e±0.004 4.410f±0.003 43.392* 0.0120
     Lung 1.776a±0.008 5.224b±0.003 2.529c±0.0008 8.446d±0.011 1.391e±0.009 2.387f±0.004 16.957* 0.00729
Glutathione Reductase                
(milli IU/mg protein)                
     Stomach 10.60a±0.006 4.800b±0.009 8.701c±0.013 7.001d±0.006 1.20e±0.005 10.90f±0.042 5.0952* 0.06612
     Lung 2.179a±0.002 0.936b±0.001 6.039c±0.003 3.4705d±0.008 2.873e±0.006 1.5752f±0.008 10.6006* 0.01417
Lactate Dehydrogenase                
(milli IU/mg protein)                
     Stomach 36.040a±0.058 17.180b±0.001 55.640c±0.005 17.730d±0.014 10.947e±0.019 32.630f±0.024 11.229* 0.0256
     Lung 13.016a±0.005 10.744b±0.005 13.19c±0.005 10.997d±0.019 11.166e±0.020 10.011f±0.010 8.186* 0.0127

*Represents significance at P≤0.05. Superscripts a-f represents comparison of group I, II, III, IV, V and VI means using HSD value.