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Age at diagnosis and death in 4S neuroblastoma (n = 49). (A) Histogram showing the frequency of patients enrolled in each age group and the number of patients who died within that group. (B) Histogram of ANBL0531 enrollment showing the frequency of symptomatic patients in each age group and the number of patients who died of acute hepatomegaly complications (n = 5). No deaths occurred from hepatomegaly for 31 patients enrolled after the June 30, 2009, protocol amendment.
